Bryn Mawr Dermatology

Villanova, PA | Collegeville, PA
Chesterbrook, PA

Ozempic Face: What It Is and How to Treat It?


In the final three months of 2022 alone, healthcare providers in the US issued over 9 million prescriptions for Ozempic, a medication primarily prescribed for type 2 diabetes patients. Were all these prescriptions meant for diabetes patients? No, Ozempic is a drug that went viral for its significant weight loss benefits, attracting a broader audience beyond those with diabetes. This medication works by slowing down how quickly the stomach empties, enhancing the feeling of fullness. It is reported that Ozempic contributes to weight reduction of about 15 to 20 percent in overweight individuals. While Ozempic is FDA-approved, clinicians and users around the world have noticed some unpleasant side effects of the drug, one of which is referred to as “Ozempic Face.”  

Ozempic Face is a condition that has sparked discussions among users and healthcare professionals alike. It refers to facial changes due to rapid weight loss from using Ozempic, including thinning and sagging skin. In this article, we at Bryn Mawr Dermatology (BMD) will share everything you need to know about Ozempic face, including its characteristics, treatment options, and prevention strategies. We aim to guide you through understanding this condition and exploring effective solutions to manage and prevent its effects.

While this article spells out some important information about Ozempic Face, we highly recommend you read the full article, here are the key points we will focus on:

Table of Contents

Ozempic Face

What is Ozempic Face?

The term’ Ozempic Face’ emerged from noticeable changes in facial features among some users, primarily wrinkling and sagging around key areas of the face, such as the eyes, temples, jawline, and mouth. Facial fat loss is particularly noticeable because the face doesn’t uniformly lose fat in response to weight loss; some areas may lose fat more rapidly than others, leading to an uneven appearance.  Moreover, the rapid weight loss effect of Ozempic can be more pronounced in middle-aged or older individuals, where the skin’s natural elasticity is reduced, and the capacity for the skin to rebound after significant fat loss diminishes. This combination of factors contributes to developing the Ozempic Face, highlighting the importance of considering the aesthetic implications of rapid weight loss treatments alongside their health benefits.

What Does Ozempic Face Look Like?

Ozempic face results in distinct alterations in facial appearance, directly resulting from the rapid loss of facial fat. These changes include:
  • Pronounced sagging of the facial skin: As the facial fat diminishes, the skin may begin to droop, lacking the underlying support it once had. This sagging is often most noticeable along the jawline and cheeks.
  • Hollowing of areas around the cheeks and eyes: The volume loss in these areas can lead to a sunken appearance, particularly noticeable below the cheekbones and under the eyes, where fat loss accentuates the hollows.
  • Appearance of fine lines and wrinkles due to volume loss: With decreased facial volume, existing lines and wrinkles can become more pronounced, and new ones may appear as the skin loses its plump, smooth texture.
  • A generally more aged appearance than before using Ozempic: Collectively, these changes contribute to an overall appearance that may seem significantly older than the individual’s chronological age before using the medication.

How Can You Treat Ozempic Face?

The experts at Bryn Mawr Dermatology can offer you a variety of ways to counter the effects of dramatic weight loss; however, we’ve found that the key component of correcting the symptoms of facial fat loss is to get treatment throughout the course of your weight loss journey.

We offer a range of treatments beyond fillers tailored to combat the effects of Ozempic Face and restore a more youthful and revitalized appearance.

1. Tightening the skin surface and improving the texture.

  • Sofwave, a cutting-edge, non-invasive ultrasound treatment that targets the skin’s mid-dermal layer to stimulate collagen production without downtime. FDA-cleared for lifting the brow, chin, jawline, and neck and reducing fine lines and wrinkles, Sofwave is perfect for those seeking rapid improvements in skin tightness and youthfulness without the inconvenience of recovery time.
  • Ultherapy, a non-invasive cosmetic procedure, offers promising solutions for individuals experiencing the effects of rapid weight loss. Sudden and significant weight loss can often lead to loose or sagging skin, particularly in the face, neck, and abdomen. Ultherapy uses focused ultrasound energy to stimulate collagen production deep within the skin, promoting natural tightening and lifting over time. By targeting the underlying layers without surgery, Ultherapy can effectively address skin laxity, restoring a youthful and toned appearance.
  • Morpheus8 combines the benefits of microneedling with radiofrequency energy to provide fractional resurfacing and subdermal renewal. This treatment penetrates deeper than traditional microneedling, targeting the underlying layers of the skin to remodel collagen effectively. Morpheus8 is versatile, capable of addressing concerns on the face and body, and is especially effective for tightening loose skin,reducing the appearance of fine lines and wrinkles, and it can target and eliminate discrete facial fat pockets

2. Replacing Volume Loss

  • Dermal fillers can be used to effectively fill in the areas where fat loss and volume loss has occurred in the face. By strategically injecting dermal fillers into areas where volume loss has occurred, such as the cheeks, temples, or under-eye area, a skilled practitioner can restore facial volume and contour, helping to mitigate the hollow or gaunt appearance sometimes associated with Ozempic use. This approach can effectively rejuvenate the face, providing a fuller, more youthful look while minimizing the visible effects of fat loss.
  • Sculptra Aesthetic stands out among our offerings for its unique approach to facial rejuvenation. Unlike immediate fillers, Sculptra gradually stimulates the body’s own collagen production. This helps restore lost facial volume and improves skin texture over time, providing a natural, more youthful-looking appearance. Sculptra is ideal for patients looking for long-term results, with lasting effects up to two years.


At BMD, we aim to provide personalized care that caters to each patient’s unique needs and desired outcomes. We understand the importance of feeling confident in your appearance, and our team is dedicated to helping you achieve the best possible results. 

How to Prevent Ozempic Face?

Preventing Ozempic Face is a crucial consideration for individuals using Ozempic for diabetes management or weight loss, aiming to mitigate the aesthetic side effects while reaping the health benefits. It’s essential to see a dermatologist throughout your weight loss journey as they can effectively offer insights into managing these changes.  They can advise on skincare routines to maintain skin health during weight loss and address any concerns about changes in facial appearance. Additionally, they can help you understand the expected effects of weight loss medications like Ozempic and monitor your progress to ensure your weight loss and overall health are on track. 

Effective prevention strategies involve a combination of lifestyle adjustments, skincare practices, and possibly medical interventions:

  • Gradual Weight Loss: Aim for a slow and steady weight loss plan to allow the skin time to adjust and minimize rapid changes in facial volume.
  • Balanced Nutrition: Ensure your diet includes sufficient vitamins, minerals, and hydration for skin elasticity and health.
  • Skincare Routine: Implement a skincare regimen with moisturizing and products designed to enhance collagen production and skin elasticity.
  • Sun Protection: Regular use of sunscreen can protect the skin from damage and support overall skin health.
  • Regular Check-ups: Consult a healthcare provider to monitor your progress and adjust your treatment plan to support health and aesthetic goals.

Is Ozempic Face Permanent?

While the skin drooping skin, eye hollows, and wrinkles caused by using a weight loss solution like Ozempic can be concerning, they are not necessarily permanent. With proper intervention, including aesthetic treatments and lifestyle adjustments, individuals can significantly improve the appearance of the Ozempic Face while maintaining their weight loss goals.  Clinical studies and patient cases have shown positive outcomes with the treatments mentioned above.

How Bryn Mawr Dermatology Can Help Treat Ozempic Face?

Bryn Mawr Dermatology (BMD) stands ready with cutting-edge treatments and personalized care for individuals dealing with Ozempic Face. We delve into the specifics of this condition, offering insights into its causes, visual indicators, and effective management strategies. BMD distinguishes itself through a commitment to individualized treatment plans, utilizing advanced technologies and techniques to address each patient’s unique needs. 

Our approach is holistic, focusing on treatment and our patients’ overall well-being and satisfaction. Whether through Dermal Fillers, Sculptra, Sofwave, and/or Morpheus8 we aim to provide a spectrum of options to combat the aesthetic challenges Ozempic poses. Don’t let Ozempic Face affect your confidence. Reach out to us for a consultation where our experts will craft a personalized treatment plan suited to your needs. Visit our website or call us at (610) 525-7800 to discover how we can help you achieve a rejuvenated appearance. 

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Bryn Mawr Dermatology

Content Review Committee at Bryn Mawr Dermatology

Led by Board Certified Dermatologist, Christine Stanko, MD, FAAD, Bryn Mawr Dermatology incorporates a patient-focused outlook in every decision since we first opened our doors on the Main Line in 2005.

By: Bryn Mawr Dermatology, Published: February 24, 2024
Medically Reviewed By: Christine Stanko, MD, FAAD – February 24, 2024

Your Skin is Our Business.



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